Florfenicol powder

Florfenicol (Florfenicol), also known as fluprofen and thiamphenicol, is a new broad-spectrum chloramphenicol for

animals that was successfully developed in the late 1980s. It is mainly used for bacterial diseases of pigs, chickens

and fish caused by sensitive bacteria, especially for respiratory infections and intestinal infections, and has been widely

used in domestic animal husbandry.

Florfenicol has a variety of preparation products, such as premixes, soluble powders, and injections. Different preparations

have different application purposes, and there are also certain differences in efficacy. Florfenicol premix, soluble powder,

and injection have 70%, 90%, and 93.3% effective rates for chicken colibacillosis, respectively. Therefore, soluble powder

and injection have the best control effect, and premix can be used as a preventive medicine. Or early treatment of mild

infections. This also shows that the water solubility of florfenicol will affect its bioavailability. With the advancement of

domestic breeding technology and concepts, more and more farms use drinking water dosing equipment to achieve

this purpose. This greatly improves the convenience of manual operation, and on the other hand, it can also greatly

improve the speed Timeliness of treatment. This not only places requirements on dosing and drinking equipment, but

also challenges the solubility of drugs. Improving the water solubility of florfenicol has become one of the current research

hotspots in the veterinary drug market.

Result：The inclusion technology of Shenglefu has good fat solubility and is easier to penetrate gastrointestinal biomembranes.

In conclusion：Shandong Shengli Biotech Co., Ltd. perfectly combines the water solubility, diffusibility and fat solubility of

florfenicol to make the absorption of florfenicol more thorough.

【New value of product】

Shandong Shengli Biotech Co., Ltd., with its unique combination of water solubility, diffusibility and fat solubility, brings

unprecedented value to clinical users.

• This product has higher solubility

Solubility reaches 3500ppm at room temperature; 6000ppm is completely dissolved in warm water at 40℃.

• Absorption is more complete
  

The unique inclusion technology increases the residence time of the drug in the intestinal tract, improves the water solubility,

diffusibility and fat solubility of the drug, and makes it easier for the drug to penetrate the gastrointestinal biomembrane and

be absorbed more thoroughly.

• More convenient for clinical use

This product dissolves quickly when added to water, does not float, does not stick to the wall, and does not block the water line;

because the carrier does not contain sugar, it is not easy to breed bacteria on the water line, which is more healthy! It fully meets

the use of the dosing device in large-scale farms.

• High temperature resistance
  

The content of heating at 105°C will not decrease, so it can be used with confidence during the clinical preparation of pellets.

• More economical to use
  

Due to the high bioavailability and excellent clinical effects of Shenglefu, there is no need to increase the use, reduce the comprehensive

use cost, and ensure the maximization of breeding benefits.

• Safe and low residue
  

Acute toxicity test results show that the LD50 of this product is 10177mg·kg-1. According to the acute toxicity classification standard of

chemical substances promulgated by WHO, it can be known that this product belongs to the actual non-toxic level (LD50 reaching

5001mg·kg-1 is actually non-toxic Level), which can ensure the safety of clinical use.